New Research Identifies Breast Cancer Marker

A new study says women with a strong family history of breast cancer should be tested for a
mutation of PALB2.

Carriers of the mutation are 35-percent more likely to develop breast cancer by the age of 70.

"In comparison, women with BRCA 1 mutation have a 50 to 70-percent chance of developing breast cancer by that age, and BRCA 2 carriers have a 40 to 60-percent chance", said Gina Morss-Fischer, with the Susan G. Komen Memorial Affiliate in Peoria.

Morss-Fischer says testing for PALB2 could be especially important for women with family history of breast cancer diagnosis before 40.

The study on PALB2 mutation was published in the latest issue of the New England Journal of Medicine was funded in part by the Susan G. Komen Foundation.

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